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Archive - Jul 13, 2020

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International Society for Extracellular Vesicles (ISEV) Announces 39 Scholarship Winners for ISEV 2020 Virtual Annual Meeting (July 20-22) on Extracellular Vesicles, Including Exosomes

On July 13, 2020, the International Society for Extracellular Vesicles (ISEV) Annual Meeting (ISEV2020), including exosomes, is now VIRTUAL (July 20-22); and will feature over 600 Discussions (Plenary Addresses, Panel Sessions, Featured Abstracts, Oral Abstract Talks, Poster Chats, & Education Sessions). The program can viewed here (https://www.isev.org/mpage/2020Program) and registration can be done here (https://www.isev.org/mpage/2020Registration). For past annual meetings, the ISEV has awarded meeting scholarships to outstanding young investigators. This year, in addition to the Young Investigator Scholarship category, ISEV has introduced three new scholarship categories: New Parent Member Scholarship (with children up to 8 years of age); Travel Scholarship for Attendees Working in World Bank Low-Income Countries; and Scholarship for Student Hardship (this category is for students who faced exceptional hardship in their careers to achieve their goals). This year’s 39 scholarship winners are listed below, together with their academic affiliations, and the titles and numbers of their abstracts for the meeting. LINA ANTOUNIANS, The Hospital for Sick Children, Canada, Abstract Title: “Epigenetic Regulation of Fetal Hypoplastic Lungs by Amniotic Fluid Stem Cell Derived Extracellular Vesicles” (OT10.4). ISHARA ATUKORALA (photo), La Trobe University, Australia, Abstract Title: “Ubiquitin E3 Ligase NEDD4 Is a Novel Regulator of Exosome Biogenesis and Secretion” (OT09.1). SOUNAK BAGCHI, Texas Tech University Health Sciences Center, USA, Abstract Title: “Bioengineered Exosomes As Novel Drug Carriers for Targeting HIV-1 Infection in the CNS” (OS29.2).

Gut Microbiota May Provide Clues for Detecting, Preventing, and Treating Type 2 Diabetes (T2D); Reduced Potential of Butyrate Production Noted in Prediabetes or Untreated T2D; Butyrate Produced Mainly by Beneficial Bacteria in Digestion of Dietary Fibers

The individual mix of microorganisms in the human gastrointestinal tract provides vital clues as to how any future incidence of type 2 diabetes can be predicted, prevented and treated. This is demonstrated in a population study led from the University of Gothenburg. That a person’s gut microbiota can contribute to type 2 diabetes has been shown in previous research, led by Fredrik Bäckhed, PhD, Professor of Molecular Medicine at Sahlgrenska Academy, University of Gothenburg in Sweden. The present study, published online on July 10, 2020 in Cell Metabolism (https://www.cell.com/cell-metabolism/fulltext/S1550-4131(20)30312-0), describes newly discovered clues in the microbiota as to how bacteria may contribute to type 2 diabetes and potentially predict who will develop disease based on an individual’s gut microbiota. The Cell Metabolism article is titled “The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study.” By studying people who have not yet developed type 2 diabetes, the researchers were able to rule out the possibility that the gut microbiota was affected by the disease or its treatment. The majority of previous studies in this field have compared healthy individuals with patients. What has emerged is that in individuals with raised fasting blood glucose levels or reduced glucose tolerance, a condition known as prediabetes, as well as in people with untreated type 2 diabetes, the gut microbiota is changed.