Syndicate content

New Probe Permits Better Visualization of Single RNA Molecules

A new type of probe that allows researchers to visualize single molecules of RNA within living cells more easily than by existing methods has been developed by biomedical engineers at Georgia Tech and collaborating institutions. "The probes we designed shine bright, are small and easy to assemble, bind rapidly to their targets, and can be imaged for hours. These characteristics make them a great choice for studying the movement and location of RNA inside a single cell and the interaction between RNA and binding proteins," said Philip Santangelo, an assistant professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, and a co-author of the article published online in Nature Methods on April 6.