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”Zone in with Zon” on Long Non-Coding RNAs, Linear and Circular

In the latest posting on his popular “Zone in with Zon” blog, Dr. Gerald Zon discusses the fascinating topic of long non-coding RNAs (lncRNAs), which now apparently also include circular non-coding RNAs. Dr. Zon describes lncRNAs as “a structurally and functionally wondrous class of nucleic acids.” He further characterizes them as “like a box of chocolates for molecular biologists.” Dr. Zon begins by defining lncRNAs and then discussing the ongoing controversy over the role(s) of these special molecules. He ends his stimulating discussion with a description of the recent discovery of thousands of well-expressed, stable, circular non-coding RNAs (circRNAs) that often show developmental-stage-specific expression. This latest Zon blog was posted on June 17, 2013. Dr. Zon is an eminent nucleic acid chemist and Director of Business Development at TriLink BioTechnologies in San Diego, California. [Zon blog post]