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Dr. Amanda Paulovich Wins 2015 “Distinguished Achievement in Proteomic Sciences” Award for Work on MRM-MS Technology to Detect Multiple Proteins Simultaneously; New Technology Advances Clinical Precision Medicine

On August 13, 2015, it was announced that The Human Proteome Organization had named Amanda Paulovich, M.D., Ph.D., as the winner of its 2015 Distinguished Achievement in Proteomic Sciences Award. “This is a great honor and a testament to the hard work of my interdisciplinary team over the past 12 years. It is really a team award,” said Dr. Paulovich, who is a member of Fred Hutchinson Cancer Research Center’s Clinical Research Division, Director of the Hutch’s Early Detection Initiative, and an Associate Professor in the Department of Medicine/Division of Oncology at the University of Washington School of Medicine in Seattle, Washington. The award recognizes a scientist for distinguished scientific achievements in the field of proteomics. It will be presented during the HUPO 2015 Vancouver CongressSeptember 27-September 30, 2015 (https://www.hupo.org/events/hupo-14th-annual-world-congress-vancouver-20...), the organization’s 14th annual worldwide meeting. Dr, Paulovich and her lab have played a major role in the development of an efficient, high-powered, precise method to detect and measure proteins in biological samples, called multiple reaction monitoring mass spectrometry *(MRM-MS). Named “Method of the Year” for 2012 by Nature Methods (http://www.nature.com/nmeth/journal/v10/n1/full/nmeth.2329.html), MRM-based proteomic assays have the potential to overcome a serious problem in biomedical research, i.e., a lack of reliable, standardizable tests for studying human proteins. Proteins carry out most biological functions in the body – including driving cancer –and are the targets of most drugs. However, a lack of robust assay platforms for studying proteins has rendered the human proteome largely inaccessible to clinical research, which is an obstacle to developing novel diagnostics and therapeutics. Widely available MRM-MS-based proteomics assays, Dr. Paulovich envisions, will transform the research enterprise, increasing the reproducibility of preclinical research, and greatly advancing the development of precision-medicine approaches to detect and treat disease.

[Press release] ["Method of the Year 2012" Nature Methods 2013 article] ["Targeted Proteomics" Nature Methods 2013 abstract] ["Proteomics Meets the Scientific Method" Nature Methods 2013 abstract]